Understanding Loss and Grief Loss can come in many forms: the death of a loved one, the end of a relationship, losing a job, or even a change in health. Grief is the natural response to loss. It affects your emotions, thoughts, and body. Grief is not a linear process. It can come in waves and vary in intensity. Common feelings include sadness, anger, confusion, guilt, and loneliness. Physical symptoms like fatigue, changes in appetite, or trouble sleeping are also common. Rec